Evidence organized by indication, not by document type.
Peer-reviewed publications, lot-characterized datasheets, and indication-indexed protocols — assembled so you can move from validation data to procurement without redundant qualification work.
Each model backed by published data.
Stromal architecture predicts cytarabine resistance in AML ex vivo
Hematopoietic suppression quantified in a validated MDS marrow construct
Bone marrow toxicity prediction: a translational ex vivo framework
Leukemia Research, 2023. Demonstrates that disease-specific stromal co-culture reproduces niche-mediated drug resistance profiles absent in conventional suspension assays.
Haematologica, 2023. Lot-to-lot characterization against defined MDS disease profiles confirms consistent hematopoietic suppression endpoints across independent compound screens.
Toxicological Sciences, 2024. Cross-model benchmarking against clinical hematotoxicity outcomes demonstrates predictive accuracy exceeding standard colony-forming unit assays.
Lot characterization data included in every document.
Indexed by indication and assay type.
Each technical datasheet includes lot-specific flow cytometry panels, recommended compound control benchmarks, and validated assay endpoints. Application notes cover drug screening and combination therapy configurations.
Protocols are organized so you can locate the relevant procedure by disease indication — AML, MDS — then filter by assay category: viability, colony formation, flow cytometry, or cytokine profiling.
Each protocol specifies seeding density, incubation parameters, and positive control compound concentrations verified against lot characterization records.
Available documents: AML Niche Model Datasheet, MDS Niche Model Datasheet, Hematotoxicity Screening App Note, Combination Therapy Protocol.
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